Article
The F-box protein gene exo-1 is a target for reverse engineering enzyme hypersecretion in filamentous fungi.
Proceedings of the National Academy of Sciences of the United States of America - 29 Jun 2021
Gabriel Raphael, Thieme Nils, Liu Qian, Li Fangya, Meyer Lisa T, Harth Simon, Jecmenica Marina, Ramamurthy Maya, Gorman Jennifer, Simmons Blake A, McCluskey Kevin, Baker Scott E, Tian Chaoguang, Schuerg Timo, Singer Steven W, Fleißner André, Benz J Philipp
Abstract excerpt
Carbohydrate active enzymes (CAZymes) are vital for the lignocellulose-based biorefinery. The development of hypersecreting fungal protein production hosts is therefore a major aim for both academia and industry. However, despite advances in our understanding of their regulation, the number of promising candidate genes for targeted strain engineering remains limited. Here, we resequenced the genome of the...
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