[Leber's optic neuropathy: new diagnostic prospects].

Article

[Leber's optic neuropathy: new diagnostic prospects].

Journal francais d'ophtalmologie - 1 Jan 1992

Pagot V, Malecaze F, Rötig A, Simorre V, Maillard P, Mathis A, Munnich A

Abstract excerpt

The diagnosis of Leber's hereditary optic neuropathy, essentially based on a family history of a similar illness, becomes difficult in sporadic cases. In this disease, mitochondrial DNA mutations have been recently discovered and detected by digestion with restriction enzyme after amplification b...

Topics

Adult
DNA Mutational Analysis
DNA, Mitochondrial
Humans
Male
Mutation
Optic Atrophies, Hereditary
Polymerase Chain Reaction

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.