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Article

[Molecular genetic analysis for Leber's hereditary optic neuropathy (LHON)].

Nihon rinsho. Japanese journal of clinical medicine - 1 Sept 1993

Tanno Y, Yoneda M, Tanaka K, Tsuji S

Abstract excerpt

Leber's hereditary optic neuropathy (LHON) is a maternally inherited disease characterized of acute visual loss predominantly affecting young men. So far twelve mutations in the mitochondrial DNA have been associated in this disease. We reviewed these mutations, and showed methods to detect these mutations which are being used in our laboratory. Seven mutations (nps 3460, 5244, 7444, 11778, 13708, 15257, 15812)...

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PMID: 8411719

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[Molecular genetic analysis for Leber's hereditary optic neuropathy (LHON)].PMID 8411719Read ↗

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[Leber's optic neuropathy: new diagnostic prospects].Semantic proximity Read ↗

[New mitochondrial DNA mutation in Leber's hereditary optic neuropathy: A case report].Semantic proximity Read ↗

[Positive diagnosis of Leber's hereditary optic neuropathy using molecular genetics].Semantic proximity Read ↗

Leber's hereditary optic neuropathy: clinical and molecular genetic aspects. Preliminary results in our families.Semantic proximity Read ↗

Leber's hereditary optic neuropathy. New genetic considerations.Semantic proximity Read ↗

Sequence analysis of the complete mitochondrial genome in patients with Leber's hereditary optic neuropathy lacking the three most common pathogenic DNA mutations.Semantic proximity Read ↗

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