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Article

[Clinical examination of Leber hereditary optic neuropathy in patients with the same gene mutation].

Przeglad lekarski - 1 Jan 2002

Chelstowska Joanna, Mroczek Katarzyna, Niebudek Dorota, Małecka-Idzikowska Alicja, Bartnik Ewa, Hanna Nizankowska Maria, Sasiadek Maria

Abstract excerpt

Leber hereditary optic neuropathy (LHON), which is a relatively rare disease, is an inherited form of bilateral atrophy of optic nerves. This atrophy is related to degeneration of retinal ganglion cells and optic nerve axons. The aetiology of this disease is complex and involves primary mutations of mitochondrial DNA, as well as secondary genetic and/or epigenetic changes. We compared the clinical course of LHON...

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Identifiers

PMID: 12632910

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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