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Article

A screen for nigericin-resistant yeast mutants revealed genes controlling mitochondrial volume and mitochondrial cation homeostasis.

Genetics - 1 Oct 2005

Kucejova Blanka, Kucej Martin, Petrezselyova Silvia, Abelovska Lenka, Tomaska Lubomir

Abstract excerpt

Little is known about the regulation of ion transport across the inner mitochondrial membrane in Saccharomyces cerevisiae. To approach this problem, we devised a screening procedure for facilitating the identification of proteins involved in mitochondrial ion homeostasis. Taking advantage of the growth inhibition of yeast cells by electroneutral K(+)/H(+) ionophore nigericin, we screened for genetic mutations...

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Identifiers

PMID: 16020778
DOI: 10.1534/genetics.105.046540
PMCID: PMC1456768

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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