Article
Prevalence of parkin gene mutations and variations in idiopathic Parkinson's disease.
Parkinsonism & related disorders - 1 Sept 2005
Sinha Rashmi, Racette Brad, Perlmutter Joel S, Parsian Abbas
Abstract excerpt
Mutations in the parkin gene are a common cause of autosomal recessive juvenile parkinsonism (AR-JP) but their role in idiopathic Parkinson's disease (PD) is not clear. Recent studies demonstrate that most young onset PD without family history is not due to mutations in parkin. However, there is less information about the role of this gene in older onset PD. The objective of the present study was to evaluate the...
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