Article
Delineation of the minimal commonly deleted segment and identification of candidate tumor-suppressor genes in del(9q) acute myeloid leukemia.
Genes, chromosomes & cancer - 1 Nov 2005
Sweetser David A, Peniket Andrew J, Haaland Christina, Blomberg Adam A, Zhang Yuntian, Zaidi Syed Tanweer, Dayyani Farshid, Zhao Zheng, Heerema Nyla A, Boultwood Jacqueline, Dewald Gordon W, Paietta Elisabeth, Slovak Marilyn L, Willman Cheryl L, Wainscoat James S, Bernstein Irwin D, Daly Sarah B
Abstract excerpt
Deletion of the long arm of chromosome 9, del(9q), is a recurring chromosomal aberration in acute myeloid leukemia (AML) that is frequently associated with t(8;21). The critical gene products affected by del(9q) are unknown but likely cooperate with the AML1/ETO fusion gene created by t(8;21) in...
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