Article
The evolution of meiosis: recruitment and modification of somatic DNA-repair proteins.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Aug 2005
Marcon Edyta, Moens Peter B
Abstract excerpt
Several DNA-damage detection and repair mechanisms have evolved to repair double-strand breaks induced by mutagens. Later in evolutionary history, DNA single- and double-strand cuts made possible immune diversity by V(D)J recombination and recombination at meiosis. Such cuts are induced endogenously and are highly regulated and controlled. In meiosis, DNA cuts are essential for the initiation of homologous...
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