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Article

A cluster of cholesterol-related genes confers susceptibility for Alzheimer's disease.

The Journal of clinical psychiatry - 1 Jul 2005

Papassotiropoulos Andreas, Wollmer M Axel, Tsolaki Magdalini, Brunner Fabienne, Molyva Dimitra, Lütjohann Dieter, Nitsch Roger M, Hock Christoph

Abstract excerpt

OBJECTIVE: Polygenic diseases are related to the complex interplay of genetic variations. We evaluated whether clusters of cholesterol- and lipid-related genetic variations are associated with Alzheimer's disease. METHOD: We analyzed 12 cholesterol-related single nucleotide polymorphisms and 48 control polymorphisms in 545 study participants (Alzheimer's disease group N = 284; control group N = 261). Diagnoses of...

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Source

Identifiers

PMID: 16013913

Genes

APOE
APOA4
LIPA
LPL
OLR1
SOAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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