Article
Immune tolerance in children with factors VIII and IX inhibitors: a single centre experience.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jul 2005
Mathias M, Liesner R, Hann I, Khair K
Abstract excerpt
Alloimmune FVIII and FIX inhibitors are the most serious complication of haemophilia in the postviral contamination era and their optimal management remains controversial. We present 15 boys with severe haemophilia (14 with haemophilia A and 1 with haemophilia B) who have received immune tolerance at our centre over a 9-year period. Twelve of them (80%) were successfully tolerized with varying dose intensities,...
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