Article
Age at first treatment and immune tolerance to factor VIII in severe hemophilia.
Thrombosis and haemostasis - 1 Mar 2003
van der Bom Johanna G, Mauser-Bunschoten Eveline P, Fischer Kathelijn, van den Berg H Marijke
Abstract excerpt
Findings from a recent study suggest that earlier start of treatment with factor VIII in patients with severe hemophilia is associated with a higher risk to develop inhibitors. We set out to assess the association between age of first administration of clotting factor VIII and the risk to develop inhibitors in infants with severe hemophilia A. This work was a cohort study, carried out in the national hemophilia...
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