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Article

Empirical and theoretical phenotypic discrimination.

Journal of thrombosis and haemostasis : JTH - 1 Jul 2009

Brummel-Ziedins K E, Orfeo T, Rosendaal F R, Undas A, Rivard G E, Butenas S, Mann K G

Abstract excerpt

We have developed an integrated approach that combines empirical and computational methodologies to define an individual's thrombin phenotype. We have evaluated the process of thrombin generation in healthy individuals and individuals with defined pathologies in order to develop general criteria relevant to assess an individual's propensity for hemorrhage or thrombosis. Three complementary hypotheses have emerged...

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Identifiers

PMID: 19630796
DOI: 10.1111/j.1538-7836.2009.03426.x
PMCID: PMC3395063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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