Article
Reciprocally interacting domains of protein phosphatase 1 and focal adhesion kinase.
Molecular and cellular biochemistry - 1 Apr 2005
Bianchi Mariarita, De Lucchini Stefania, Vietri Michele, Villa-Moruzzi Emma
Abstract excerpt
Protein phosphatase 1delta (PP1delta) localizes to focal adhesions and associates with the focal adhesion kinase (FAK). In the present work we used deletion mutants of PP1delta and FAK to detect their reciprocally interacting domains. Dissection of PP1delta indicated 194-260 as the shortest FAK-interacting domain among those tested. Domain 194-260 encompasses several sites involved in catalysis, indirectly...
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