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Article

In search of genes involved in neurodegenerative disorders.

Mutation research - 30 Dec 2005

Pardo Luba M, van Duijn Cornelia M

Abstract excerpt

Dissecting the genetics of Alzheimer's disease (AD) and Parkinson's disease (PD) has contributed significantly to our understanding of the pathogenesis of neurodegeneration in these two complex disorders. For AD, three highly penetrant genes (amyloid precursor protein (APP, PSEN1 and PSEN2) and one susceptibility gene (APOE) have been identified. For PD, seven genes (SNCA, Parkin, UCHL1, NR4A2, DJ1, PINK1 and...

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Source

Identifiers

PMID: 16009383
DOI: 10.1016/j.mrfmmm.2005.06.006

Genes

APOE
APP
PINK1
PSEN1
PSEN2
SNCA
UCHL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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