Article
Identification of functional candidate genes for body composition by expression analyses and evidencing impact by association analysis and mapping.
Biochimica et biophysica acta - 25 Jul 2005
Ponsuksili Siriluck, Murani Eduard, Schellander Karl, Schwerin Manfred, Wimmers Klaus
Abstract excerpt
This study aims to identify hepatic genes affecting traits related to muscularity and obesity by combining expression analyses, association studies, and gene mapping. Functional candidate genes with trait-associated expression were obtained by hybridising custom made application-specific cDNA microarrays with targets of discordant sib pairs of a porcine experimental population. Out of 238 genes addressed, nine...
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