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Integrating expression profiling and whole-genome association for dissection of fat traits in a porcine model.

Journal of lipid research - 1 Apr 2011

Ponsuksili S, Murani E, Brand B, Schwerin M, Wimmers K

Abstract excerpt

Traits related to fatness, important as economic factors in pork production, are associated with serious diseases in humans. Genetical genomics is a useful approach for studying the effects of genetic variation at the molecular level in biological systems. Here we applied a whole-genome association analysis to hepatic gene expression traits, focusing on transcripts with expression levels that correlated with...

Topics

Animals
Fats
Gene Expression Profiling
Genome-Wide Association Study
Genotype
Lipid Metabolism
Quantitative Trait Loci
Signal Transduction
Swine

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21289033
DOI: 10.1194/jlr.M013342
PMCID: PMC3284160

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