Article
Importance of randomization in microarray experimental designs with Illumina platforms.
Nucleic acids research - 1 Sept 2009
Verdugo Ricardo A, Deschepper Christian F, Muñoz Gloria, Pomp Daniel, Churchill Gary A
Abstract excerpt
Measurements of gene expression from microarray experiments are highly dependent on experimental design. Systematic noise can be introduced into the data at numerous steps. On Illumina BeadChips, multiple samples are assayed in an ordered series of arrays. Two experiments were performed using the same samples but different hybridization designs. An experiment confounding genotype with BeadChip and treatment with...
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