Article
The phagosomal transporter A couples threonine acquisition to differentiation and replication of Legionella pneumophila in macrophages.
Proceedings of the National Academy of Sciences of the United States of America - 12 Jul 2005
Sauer John-Demian, Bachman Michael A, Swanson Michele S
Abstract excerpt
Differentiation in response to environmental cues is integral to the success of many intracellular pathogens. By characterizing a Legionella pneumophila mutant defective for differentiation in broth and replication in macrophages, we identified a subfamily of major facilitator superfamily transporters, here named Pht (phagosomal transporter), that also is conserved in two other vacuolar pathogens, Coxiella...
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