Article
Legionella pneumophila couples fatty acid flux to microbial differentiation and virulence.
Molecular microbiology - 1 Mar 2009
Edwards Rachel L, Dalebroux Zachary D, Swanson Michele S
Abstract excerpt
During its life cycle, Legionella pneumophila alternates between at least two phenotypes: a resilient, infectious form equipped for transmission and a replicative cell type that grows in amoebae and macrophages. Considering its versatility, we postulated that multiple cues regulate L. pneumophila differentiation. Beginning with a Biolog Phenotype MicroArray screen, we demonstrate that excess short-chain fatty...
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