Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Changes in human immunodeficiency virus type 1 fitness and genetic diversity during disease progression.

Journal of virology - 1 Jul 2005

Troyer Ryan M, Collins Kalonji R, Abraha Awet, Fraundorf Erika, Moore Dawn M, Krizan Randall W, Toossi Zahra, Colebunders Robert L, Jensen Mark A, Mullins James I, Vanham Guido, Arts Eric J

Abstract excerpt

This study examined the relationship between ex vivo human immunodeficiency virus type 1 (HIV-1) fitness and viral genetic diversity during the course of HIV-1 disease. Primary HIV-1 isolates from 10 patients at different time points were competed against control HIV-1 strains in peripheral blood mononuclear cell (PBMC) cultures to determine relative fitness values. Patient HIV-1 isolates sequentially gained...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acquired Immunodeficiency Syndrome
Share to Anti-HIV Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD4 Lymphocyte Count

Share to Disease Progression

Share to Heteroduplex Analysis

Share to Receptors, HIV

Share to Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 15994794
DOI: 10.1128/JVI.79.14.9006-9018.2005
PMCID: PMC1168764

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Changes in human immunodeficiency virus type 1 fitness and genetic diversity during disease progression.PMID 15994794Read ↗

A Dual Infection/Competition Assay Shows a Correlation between Ex Vivo Human Immunodeficiency Virus Type 1 Fitness and Disease ProgressionSemantic proximity Read ↗

Virus fitness: concept, quantification, and application to HIV population dynamics.Semantic proximity Read ↗

Role of Baseline pol Genotype in HIV-1 Fitness Evolution.Semantic proximity Read ↗

Differences in the Fitness of Two Diverse Wild-Type Human Immunodeficiency Virus Type 1 Isolates Are Related to the Efficiency of Cell Binding and EntrySemantic proximity Read ↗

Human immunodeficiency virus type 1 fitness and tropism: concept, quantification, and clinical relevance.Semantic proximity Read ↗

Clinical significance of human immunodeficiency virus type 1 replication fitness.Semantic proximity Read ↗

CCR5- and CXCR4-tropic subtype C human immunodeficiency virus type 1 isolates have a lower level of pathogenic fitness than other dominant group M subtypes: implications for the epidemic.Semantic proximity Read ↗

Comparing the Ex Vivo Fitness of CCR5-Tropic Human Immunodeficiency Virus Type 1 Isolates of Subtypes B and CSemantic proximity Read ↗

Viral phenotype and fitness.Semantic proximity Read ↗

Factors affecting relative fitness measurements in pairwise competition assays of human immunodeficiency viruses.Semantic proximity Read ↗

Role of the Human Immunodeficiency Virus Type 1 Envelope Gene in Viral FitnessSemantic proximity Read ↗

Can modulation of viral fitness represent a target for anti-HIV-1 strategies?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.