Article
Foamy virus Bet proteins function as novel inhibitors of the APOBEC3 family of innate antiretroviral defense factors.
Journal of virology - 1 Jul 2005
Russell Rebecca A, Wiegand Heather L, Moore Michael D, Schäfer Alexandra, McClure Myra O, Cullen Bryan R
Abstract excerpt
Foamy viruses are a family of complex retroviruses that establish common, productive infections in a wide range of nonhuman primates. In contrast, humans appear nonpermissive for foamy virus replication, although zoonotic infections do occur. Here we have analyzed the ability of primate and mouse APOBEC3G proteins to inhibit the infectivity of primate foamy virus (PFV) virions produced in their presence. We...
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