Article
Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population.
Biological psychiatry - 1 Jul 2005
Wu Suping, Jia Meixiang, Ruan Yan, Liu Jing, Guo Yanqing, Shuang Mei, Gong Xiaohong, Zhang Yanbo, Yang Xiaoling, Zhang Dai
Abstract excerpt
BACKGROUND: Previous research has suggested that the social impairments exhibited by individuals with autism are associated with changes in plasma oxytocin (OT) levels. The physiologic effects of oxytocin are mediated through its specific receptors (OTRs), and numerous studies have implicated OTRs in the regulation of social cognition and behavior. Animal models and linkage data from genome screens indicate that...
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