Article
Association of the oxytocin receptor (OXTR) gene polymorphisms with autism spectrum disorder (ASD) in the Japanese population.
Journal of human genetics - 1 Mar 2010
Liu Xiaoxi, Kawamura Yoshiya, Shimada Takafumi, Otowa Takeshi, Koishi Shinko, Sugiyama Toshiro, Nishida Hisami, Hashimoto Ohiko, Nakagami Ryoichi, Tochigi Mamoru, Umekage Tadashi, Kano Yukiko, Miyagawa Taku, Kato Nobumasa, Tokunaga Katsushi, Sasaki Tsukasa
Abstract excerpt
The oxytocin receptor (OXTR) gene, which is located on chromosome 3p25.3, has been implicated as a candidate gene for susceptibility of autism spectrum disorder (ASD). Positive associations between OXTR and ASD have been reported in earlier studies. However, the results were inconsistent and demand further studies. In this study, we investigated the associations between OXTR and ASD in a Japanese population by...
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