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Article

Meta-analysis and association of two common polymorphisms of the human oxytocin receptor gene in autism spectrum disorder.

Autism research : official journal of the International Society for Autism Research - 1 Oct 2016

Kranz Thorsten M, Kopp Marnie, Waltes Regina, Sachse Michael, Duketis Eftichia, Jarczok Tomasz A, Degenhardt Franziska, Görgen Katharina, Meyer Jobst, Freitag Christine M, Chiocchetti Andreas G

Abstract excerpt

Neuropeptides such as oxytocin (OXT) are known facilitators of social behavior across species. Variants of the OXT receptor gene (OXTR) have been tested for association with autism spectrum disorder (ASD) across manifold ethnicities, yielding both positive and negative findings. A recent meta-analysis, comprising 16 single nucleotide polymorphisms (SNPs), has corroborated the implication of OXTR in the etiology...

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Identifiers

PMID: 26788924
DOI: 10.1002/aur.1597

Genes

OXTR
OXT

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