Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Translational research on lung cancer--EGFR gene mutation].

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Jun 2005

Kosaka Takayuki, Endoh Hideki, Yatabe Yasushi, Mitsudomi Tetsuya

Abstract excerpt

Recent reports that activating mutations of the EGFR have a significant association with the response to gefitinib drew much attention. Mutations are more frequently observed in Oriental patients, females, non-smokers and adenocarcinoma patients, which correspond to patient profiles predictive of a good clinical response with gefitinib. In vitro experiments also revealed EGFR mutant cell lines are highly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Drug Resistance, Neoplasm
Share to Gefitinib

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Kinase Inhibitors

Share to Protein-Tyrosine Kinases

Share to Quinazolines

Share to Sequence Deletion

Share to Smoking

Source

Identifiers

PMID: 15984511

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Translational research on lung cancer--EGFR gene mutation].PMID 15984511Read ↗

Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers?Semantic proximity Read ↗

Gefitinib as first-line treatment for patients with advanced non-small-cell lung cancer with activating Epidermal Growth Factor Receptor mutation: implications for clinical practice and open issues.Semantic proximity Read ↗

EGFR kinase domain mutations - functional impact and relevance for lung cancer therapy.Semantic proximity Read ↗

[Epidermal growth factor receptor (EGFR): therapeutic target in the treatment of lung adenocarcinoma].Semantic proximity Read ↗

[Mutation testing for non-small-cell lung cancer].Semantic proximity Read ↗

Trying to compose the puzzle with all the pieces: epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer.Semantic proximity Read ↗

Mutations in the epidermal growth factor receptor gene and effects of EGFR-tyrosine kinase inhibitors on lung cancers.Semantic proximity Read ↗

[Gefitinib and epidermal growth factor receptor gene mutation].Semantic proximity Read ↗

[Sampling and search for the EGFR mutation: what's taking, when and how to test?].Semantic proximity Read ↗

[EGFR-mutation in non-small cell lung carcinoma. Treatment with tyrosine kinase inhibitors possible].Semantic proximity Read ↗

[Mutational analysis of EGFR and K-RAS in Chinese patients with non-small cell lung cancer].Semantic proximity Read ↗

EGFR mutations in patients with non small-cell lung cancer in Bulgaria and treatment with gefitinib.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.