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Complement Component C1q and Anti‐C1q Antibodies in Theory and in Clinical Practice

18 Mar 2008

Abstract excerpt

The complement system is a major part of the innate immunity. The first component of the classical pathway of complement activation, C1q, plays a crucial role in the clearance of immune complexes and apoptotic bodies from the organism. Autoantibodies against C1q (anti-C1q) have been found in a number of autoimmune and infectious diseases. They have been best described in patients with systemic lupus...

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PMID: 18363591
DOI: 10.1111/j.1365-3083.2008.02089.x

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