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Article

Multiple promoter elements govern expression of the human ornithine decarboxylase gene in colon carcinoma cells.

Nucleic acids research - 25 May 1992

Moshier J A, Osborne D L, Skunca M, Dosescu J, Gilbert J D, Fitzgerald M C, Polidori G, Wagner R L, Friezner Degen S J, Luk G D

Abstract excerpt

Overexpression of the ornithine decarboxylase (ODC) gene may be important to the development and maintenance of colonic neoplasms, as well as tumors in general. In this study, we examined the promoter elements governing constitutive expression of the human ODC gene in HCT 116 human colon carcinoma cells and, for comparison, K562 human erythro-leukemia cells. It was determined by functional analysis that the...

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Identifiers

PMID: 1598217
DOI: 10.1093/nar/20.10.2581
PMCID: PMC312396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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