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Optimization of tetracycline‐responsive recombinant protein production and effect on cell growth and ER stress in mammalian cells

24 Jun 2005

Abstract excerpt

The inducible T-REx system and other inducible expression systems have been developed in order to control the expression levels of recombinant protein in mammalian cells. In order to study the effects of heterologous protein expression on mammalian host behavior, the gene for recombinant Human transferrin (hTf) was integrated into HEK-293 cells and expressed under the control of the T-REx inducible technology...

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PMID: 15981277
DOI: 10.1002/bit.20566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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