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Article

Comparison of seven different heterologous protein expression systems for the production of the serotonin transporter.

Biochimica et biophysica acta - 17 Feb 2003

Tate Christopher G, Haase Jana, Baker Cara, Boorsma Marco, Magnani Francesca, Vallis Yvonne, Williams D Clive

Abstract excerpt

The rat serotonin transporter (rSERT) is an N-glycosylated integral membrane protein with 12 transmembrane regions; the N-glycans improve the ability of the SERT polypeptide chain to fold into a functional transporter, but they are not required for the transmembrane transport of serotonin per se. In order to define the best system for the expression, purification and structural analysis of serotonin transporter...

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PMID: 12586388
DOI: 10.1016/s0005-2736(02)00719-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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