Article
Current concept of pathophysiological understanding and natural course of ulcerative colitis.
Langenbeck's archives of surgery - 1 Oct 2004
Holtmann Martin H, Galle Peter R
Abstract excerpt
INTRODUCTION: According to the current paradigm both ulcerative colitis (UC) and Crohn's disease (CD) result from a complex interplay of genetic susceptibility factors, environmental factors, alterations of the physiological intestinal flora and a defective regulation of the intestinal immune system. DISCUSSION: The objective of this review is to give an overview of these factors and mechanisms, including...
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