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Article

Inflammatory bowel disease: cause and immunobiology.

Lancet (London, England) - 12 May 2007

Baumgart Daniel C, Carding Simon R

Abstract excerpt

Crohn's disease and ulcerative colitis are idiopathic inflammatory bowel disorders. In this paper, we discuss how environmental factors (eg, geography, cigarette smoking, sanitation and hygiene), infectious microbes, ethnic origin, genetic susceptibility, and a dysregulated immune system can result in mucosal inflammation. After describing the symbiotic interaction of the commensal microbiota with the host, oral...

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Identifiers

PMID: 17499605
DOI: 10.1016/S0140-6736(07)60750-8

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Source receipt: pubmed, retrieved 7 Sept 2026.

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