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Article

HIV-1 genotypes related to failure of nelfinavir as the first protease inhibitor treatment.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Aug 2005

Tupinambás Unaí, Aleixo Agdemir, Greco Dirceu

Abstract excerpt

Combined antiretroviral therapy results in sustained viral suppression and a decrease in mortality and morbidity due to HIV infection. Intrinsic strength, durability and absence of cross-resistance are key factors in the selection of antiretrovirals. Failure with nelfinavir has been associated with two protease gene mutations, D30N and L90M. The D30N mutation does not result in cross-resistance with other...

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Identifiers

PMID: 16270125
DOI: 10.1590/s1413-86702005000400009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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