Article
Protective & risk DR phenotypes in Asian Indian patients with rheumatoid arthritis.
The Indian journal of medical research - 1 Feb 1992
Taneja V, Mehra N K, Kailash S, Anand C, Malaviya A N
Abstract excerpt
This study of 168 north Indian patients with rheumatoid arthritis (RA) confirms the significant association of susceptibility to RA with DR4 specificity (P less than 0.0001). This association was observed equally in familial as well as sporadic patients. The HLA-DR2 and DR5 alleles were identified to be conferring protection in RA, DR5 being reduced significantly in the non-familial patients only. None of the...
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