HLA-DRB1 genes and susceptibility to rheumatoid arthritis in three ethnic groups from Malaysia.

doi:10.1080/08916930290024179

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Article

HLA-DRB1 genes and susceptibility to rheumatoid arthritis in three ethnic groups from Malaysia.

Autoimmunity - 1 Jul 2002

Kong K F, Yeap S S, Chow S K, Phipps Maude E

Abstract excerpt

Worldwide population studies have generally agreed that rheumatoid arthritis (RA) is associated with a group of HLA-DRB1 alleles which share a common amino acid sequence at residues 70-74. This represents the first study to investigate the association of HLA-DRB1 genes with susceptibility to RA amongst Malay, Chinese and Indian ethnic groups in Malaysia. One hundred and thirty three RA patients and one hundred...

Topics

Alleles
Arthritis, Rheumatoid
Asian People
Gene Frequency
Genetic Predisposition to Disease
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Malaysia
Odds Ratio
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational

Source

Open in PubMed

Identifiers

PMID: 12482190
DOI: 10.1080/08916930290024179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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