Article
Comparative phenotypic and CARD15 mutational analysis among African American, Hispanic, and White children with Crohn's disease.
Inflammatory bowel diseases - 1 Jul 2005
Kugathasan Subra, Loizides Anthony, Babusukumar Umesh, McGuire Erin, Wang Tao, Hooper Pleasant, Nebel Justin, Kofman Galina, Noel Richard, Broeckel Ulrich, Tolia Vasundhara
Abstract excerpt
BACKGROUND: Despite a large body of literature on the subject of Crohn's disease (CD), very little information is available on racial/ethnic differences related to disease presentation, clinical course, and genetics. The first identified CD susceptibility gene, CARD15, seems to be present in up to 40% of white children with CD. However, the frequency of this gene among patients with CD of other racial/ethnic...
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