Article
Overexpression of the Wnt5b Gene in Leiomyoma Cells: Implications for a Role of the Wnt Signaling Pathway in the Uterine Benign Tumor
1 Sept 2005
Abstract excerpt
CONTEXT: Uterine leiomyomas are the most common tumors in the human female pelvis and the leading indication for pelvic surgery. The molecular causes of the disease remain unknown. OBJECTIVE: Using an oligonucleotide microarray-based hybridization analysis, we observed that a Wnt family member transcript, Wnt5b, was overexpressed in smooth muscle cells (SMC) derived from leiomyomas when compared with matched...
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