Article
SATB2 and NGR1: potential upstream regulatory factors in uterine leiomyomas.
Journal of assisted reproduction and genetics - 1 Nov 2019
Sato Shun, Maekawa Ryo, Tamura Isao, Shirafuta Yuichiro, Shinagawa Masahiro, Asada Hiromi, Taketani Toshiaki, Tamura Hiroshi, Sugino Norihiro
Abstract excerpt
PURPOSE: We attempted to identify the genes involved in the pathogenesis of uterine leiomyomas, under a hypothesis that the aberrant expression of upstream regulatory genes caused by aberrant DNA methylation is involved in the onset and development of uterine leiomyomas. METHODS: To find such genes, we compared genome-wide mRNA expression and DNA methylation in uterine leiomyomas and adjacent normal myometrium....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
