Article
MicroRNAs in the development and pathobiology of uterine leiomyomata: does evidence support future strategies for clinical intervention?
Human reproduction update - 1 Jan 2000
Karmon Anatte E, Cardozo Eden R, Rueda Bo R, Styer Aaron K
Abstract excerpt
BACKGROUND: Human leiomyomata (fibroids) are benign tumors of the uterus, represent the most common neoplasms of reproductive-aged women and have a prevalence of ∼70% in the general population. This disorder conveys a significant degree of morbidity and remains the leading indication for hysterectomy in the USA. Prior investigations of aberrant microRNA (miRNA) expression in various malignancies have provided...
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