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Article

Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors.

Neoplasia (New York, N.Y.) - 1 Apr 2005

Robey Ian F, Lien Anthony D, Welsh Sarah J, Baggett Brenda K, Gillies Robert J

Abstract excerpt

Metastatic tumors generally exhibit aerobic glycolysis (the Warburg effect). The advent of [18F]fluorodeoxyglucose positron emission tomography imaging, coupled with recent findings linking hypoxia-inducible factor (HIF-1alpha) overexpression to aggressive cancers, has rekindled an interest in this aspect of tumor metabolism. These studies explore the role of HIF-1alpha in human breast cancer lines and its...

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Identifiers

PMID: 15967109
DOI: 10.1593/neo.04430
PMCID: PMC1501147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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