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Article

Example of Adverse Outcome Pathway Concept Enabling Genome-to-Phenome Discovery in Toxicology.

Integrative and comparative biology - 1 Aug 2020

Gust Kurt A, Ji Qing, Luo Xiao

Abstract excerpt

The following article represents a mini-review of an intensive 10-year progression of genome-to-phenome (G2P) discovery guided by the adverse outcome pathway (AOP) concept. This example is presented as a means to stimulate crossover of this toxicological concept to enhance G2P discovery within the broader biological sciences community. The case study demonstrates the benefits of the AOP approach for establishing...

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PMID: 32516358
DOI: 10.1093/icb/icaa064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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