Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acute myeloid leukemia: therapeutic impact of epigenetic drugs.

The international journal of biochemistry & cell biology - 1 Sept 2005

Altucci Lucia, Clarke Nicole, Nebbioso Angela, Scognamiglio Annamaria, Gronemeyer Hinrich

Abstract excerpt

Acute myeloid leukemia (AML) is not a single disease but a group of malignancies in which the clonal expansion of various types of hematopoietic precursor cells in the bone marrow leads to perturbation of the delicate balance between self-renewal and differentiation that is characteristic of normal hematopoiesis. An increasing number of genetic aberrations, such as chromosomal translocations that alter the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylation
Share to Acute Disease
Share to Antineoplastic Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Epigenesis, Genetic

Share to Gene Silencing

Share to Histone Deacetylase Inhibitors

Share to Leukemia, Myeloid

Source

Identifiers

PMID: 15964234
DOI: 10.1016/j.biocel.2005.04.019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acute myeloid leukemia: therapeutic impact of epigenetic drugs.PMID 15964234Read ↗

Epigenetic Therapy in Acute Myeloid Leukemia: Current and Future Directions.Semantic proximity Read ↗

Clinical developments in epigenetic-directed therapies in acute myeloid leukemiaSemantic proximity Read ↗

Epigenetics and approaches to targeted epigenetic therapy in acute myeloid leukemiaSemantic proximity Read ↗

Recent Clinical Update of Acute Myeloid Leukemia: Focus on Epigenetic Therapies.Semantic proximity Read ↗

Epigenetic regulators and their impact on therapy in acute myeloid leukemiaSemantic proximity Read ↗

Epigenetic changes: a common theme in acute myelogenous leukemogenesisSemantic proximity Read ↗

Epigenetic regulators as promising therapeutic targets in acute myeloid leukemiaSemantic proximity Read ↗

Epigenetic alterations in acute myeloid leukemiasSemantic proximity Read ↗

Histone deacetylase inhibitors: targeting epigenetic regulation in the treatment of acute leukemiaSemantic proximity Read ↗

The evolving landscape of epigenetic target molecules and therapies in myeloid cancers: focus on acute myeloid leukemia and myeloproliferative neoplasmsSemantic proximity Read ↗

Epigenetic therapies in acute myeloid leukemia: the role of hypomethylating agents, histone deacetylase inhibitors and the combination of hypomethylating agents with histone deacetylase inhibitorsSemantic proximity Read ↗

Epigenetics in Hematological Malignancies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.