Article
Comparison of replicative senescence and stress‐induced premature senescence combining differential display and low‐density DNA arrays
8 Jun 2005
Abstract excerpt
Human diploid fibroblasts (HDFs) exposed to subcytotoxic stress display many features of senescence. Using differential display RT-PCR, gene expression of HDFs in premature senescence induced by tert-butylhydroperoxide or ethanol and in replicative senescence was compared to gene expression of HDFs at early cumulative population doublings. Thirty genes of known function were identified from the 265 differentially...
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