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Article

Stress-induced premature senescence and replicative senescence are different phenotypes, proteomic evidence.

Biochemical pharmacology - 1 Sept 2002

Dierick Jean-François, Eliaers François, Remacle José, Raes Martine, Fey Stephen J, Larsen Peter Mose, Toussaint Olivier

Abstract excerpt

In this paper, we illustrate how a proteomic analysis can be useful to approach complex biological problems, in this case the concept of stress-induced premature senescence (SIPS). According to the stochastic theories of ageing, damage that accumulate with time in the cellular components are responsible for cellular ageing. As a corollary, some sort of premature senescence should appear if the damage level is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12213600
DOI: 10.1016/s0006-2952(02)01171-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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