Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatocyte Growth Factor Gene Transfer to Alveolar Septa for Effective Suppression of Lung Fibrosis

1 May 2005

Abstract excerpt

We examined therapeutic gene transfer of human hepatocyte growth factor (hHGF) to alveolar septa in mouse bleomycin-induced lung fibrosis using macroaggregated albumin-polyethylenimine complex (MAA-PEI). Intravenous administration of MAA-PEI along with 1 microg pCAG.hHGF to C57BL/6 mice increased the uptake of plasmids into alveolar capillary endothelial cells and epithelial cells, prolonged hHGF expression in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver physiology and pathology
Share to Mesenchymal stem cell research
Share to Neonatal Respiratory Health Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15963921
DOI: 10.1016/j.ymthe.2005.02.019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatocyte Growth Factor Gene Transfer to Alveolar Septa for Effective Suppression of Lung FibrosisPMID 15963921Read ↗

Targeted Gene Transfer of Hepatocyte Growth Factor to Alveolar Type II Epithelial Cells Reduces Lung Fibrosis in RatsSemantic proximity Read ↗

Hepatocyte growth factor induces hepatocyte proliferation in vivo and allows for efficient retroviral-mediated gene transfer in miceSemantic proximity Read ↗

Amelioration of pulmonary emphysema by in vivo gene transfection with hepatocyte growth factor in rats.Semantic proximity Read ↗

Noninvasive gene delivery to the liver by mechanical massageSemantic proximity Read ↗

Sustained Expression of Naked Plasmid Dna Encoding Hepatocyte Growth Factor in Mice Promotes Liver and Overall Body GrowthSemantic proximity Read ↗

Electroporation-mediated HGF gene transfer ameliorated cyclosporine nephrotoxicity.Semantic proximity Read ↗

The hepatocyte growth factor-expressing character is required for mesenchymal stem cells to protect the lung injured by lipopolysaccharide in vivoSemantic proximity Read ↗

Antifibrotic Effect of MMP13-encoding Plasmid DNA Delivered Using Polyethylenimine Shielded With Hyaluronic AcidSemantic proximity Read ↗

Hepatocyte growth factor inhibits epithelial to myofibroblast transition in lung cells via Smad7.Semantic proximity Read ↗

Establishment of an early liver fibrosis model by the hydrodynamics-based transfer of TGF-β1 geneSemantic proximity Read ↗

Hepatocyte growth factor and melanoma: gene transfer studies in human melanocytes.Semantic proximity Read ↗

Hepatocyte Growth Factor Gene Therapy for Ischemic DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.