Article
Apolipoprotein E and progression of chronic kidney disease.
JAMA - 15 Jun 2005
Hsu Charles C, Kao W H Linda, Coresh Josef, Pankow James S, Marsh-Manzi Jane, Boerwinkle Eric, Bray Molly S
Abstract excerpt
CONTEXT: Apolipoprotein E (APOE) genetic variation has been implicated in diabetic nephropathy with the epsilon2 allele increasing and the epsilon4 allele decreasing risk. APOE allelic associations with chronic kidney disease beyond diabetic nephropathy are unknown, with no studies reported in high-risk African American populations. OBJECTIVE: To quantify the risk of chronic kidney disease progression associated...
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