Article
Type 2 diabetes mellitus and its renal complications in relation to apolipoprotein E gene polymorphism.
Translational research : the journal of laboratory and clinical medicine - 1 Sept 2008
Ma Shuk-Woon, Benzie Iris F F, Yeung Vincent T F
Abstract excerpt
The apolipoprotein E (APOE) epsilon2 allele is reported to be associated with greater risk of renal impairment in type 2 diabetes. Relationships among APOE polymorphisms, renal impairment, and biochemical parameters were explored. A prospective study of 405 consenting Chinese type 2 diabetic patients [mean age +/- standard deviation (SD): 59.2 +/- 10.3 years] without advanced complications at entry was conducted....
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