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Article

Interleukin-1 gene cluster polymorphisms predict risk of ESRD.

Kidney international - 1 Jul 2005

Wetmore James B, Hung Adriana M, Lovett David H, Sen Saunak, Quershy Omer, Johansen Kirsten L

Abstract excerpt

BACKGROUND: Patients with chronic kidney disease manifest an inflammatory state relative to healthy individuals. Inflammation is regulated in part by genes of the interleukin-1 (IL-1) gene cluster. We hypothesized that polymorphisms in this gene cluster may be associated with risk of end-stage renal disease (ESRD). METHODS: Polymorphisms in the IL-1 gene cluster were examined in a cohort of 239 racially diverse...

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Identifiers

PMID: 15954918
DOI: 10.1111/j.1523-1755.2005.00403.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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