Article
Association of an IL-1A 3'UTR polymorphism with end-stage renal disease and IL-1 alpha expression.
Kidney international - 1 Apr 2003
Bensen Jeannette T, Langefeld Carl D, Li Liwu, McCall Charles E, Cousart Susan L, Dryman Bonnie N, Freedman Barry I, Bowden Donald W
Abstract excerpt
BACKGROUND: We evaluated polymorphisms in the interleukin-1 alpha 3'-untranslated region (IL-1A 3'[UTR]) for association with type 2 diabetes-associated (DM) and nondiabetic-associated (non-DM) end-stage renal disease (ESRD) in two ethnic groups. METHODS: IL-1A 3'UTR polymorphisms were identified by alignment of overlapping human expressed sequence tags (ESTs). Sequence ambiguities were experimentally confirmed...
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