Article
Epigenetic silencing may aid evolution by gene duplication.
Journal of molecular evolution - 1 Jun 2003
Rodin Sergei N, Riggs Arthur D
Abstract excerpt
Gene duplication is commonly regarded as the main evolutionary path toward the gain of a new function. However, even with gene duplication, there is a loss-versus-gain dilemma: most newly born duplicates degrade to pseudogenes, since degenerative mutations are much more frequent than advantageous ones. Thus, something additional seems to be needed to shift the loss versus gain equilibrium toward functional...
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