Article
Distribution and phenotype of murine rotavirus-specific B cells induced by intranasal immunization with 2/6 virus-like particles.
European journal of immunology - 1 Jul 2005
Ogier Agathe, Franco Manuel A, Charpilienne Annie, Cohen Jean, Pothier Pierre, Kohli Evelyne
Abstract excerpt
Virus-like particles containing the rotavirus (RV) internal proteins VP2 and VP6 (2/6-VLP) have been shown to induce serum and fecal antibodies as well as protection in mice after intranasal administration with a mutant of E. coli toxin, LT-R192G. To better understand the origin of fecal IgA induced by this protocol, we studied the RV-specific B cell response in systemic and mucosal lymphoid tissues using a flow...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
